Full guide to No. 23 USC vs. Nebraska: How to watch, odds, injuries, and more

Nebraska got back on track against Northwestern, but now the Cornhuskers welcome No. 23 USC to town in hopes of securing the upset win.
Oct 25, 2025; Lincoln, Nebraska, USA; Nebraska Cornhuskers quarterback Dylan Raiola (15) looks to throw a pass and offensive lineman Turner Corcoran (69) blocks against the Northwestern Wildcats during the third quarter at Memorial Stadium. Mandatory Credit: Dylan Widger-Imagn Images
Oct 25, 2025; Lincoln, Nebraska, USA; Nebraska Cornhuskers quarterback Dylan Raiola (15) looks to throw a pass and offensive lineman Turner Corcoran (69) blocks against the Northwestern Wildcats during the third quarter at Memorial Stadium. Mandatory Credit: Dylan Widger-Imagn Images | Dylan Widger-Imagn Images

After a brutal loss to Minnesota two weeks ago, where nothing went right offensively for the Cornhuskers, Nebraska got back on track against Northwestern with a hard-fought 28-21 victory. Now, Nebraska will be tested again as No. 23 USC comes to town for a big nighttime showdown.

The good news for this matchup is that Nebraska isn't the team having to travel over 1,500 miles to play this game, giving them that small leg up. However, USC's passing attack is great, and the Nebraska secondary will have to be ready to go.

Nebraska has been hit with some injuries lately, especially on the offensive line, so being able to protect quarterback Dylan Raiola will be key in this game. Winning this one could be big for Nebraska, which is looking to rack up some quality wins on the season. Nebraska has yet to beat USC in its short history of playing each other, so this is a game the Cornhuskers will be desperate to get.

How to watch No. 23 USC vs. Nebraska in Week 10

  • Date: Saturday, November 1
  • Time: 6:30 p.m. CT
  • Venue: Memorial Stadium
  • How to watch (TV): NBC
  • StreamingFuboTV
  • No. 23 USC record: 5-2
  • Nebraska record: 6-2

No. 23 USC vs. Nebraska odds, spread, and total

Odds provided by FanDuel Sportsbook

Spread

  • USC: -6.5 (106)
  • Nebraska: +6.5 (114)

Moneyline

  • USC: -225
  • Nebraska: +184

Total

  • O/U: 59.5 (-110/-110)

USC injuries

  • N/A

Nebraska injuries

  • Teddy Prochazka: out
  • Gunner Gottula: questionable

Weather in Lincoln, NE

As November hits, the temperatures will continue to drop, which could be an advantage for Nebraska in this game. It will be only a high of 51 degrees on Saturday and a low of 33 degrees. With this game being played at night, those colder temperatures will definitely hit, and USC may not be prepared for it.

Announcers for No. 23 USC vs. Nebraska

The announcers for No. 23 USC vs. Nebraska has yet to be announced.

Nebraska and USC series history

Nebraska's all-time record vs. USC: 0-5-1

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